University of North Texas Health Science Center at Fort Worth
发明人:
Vishwanatha, Jamboor K.,Braden, Arthur R.C.
申请号：
AU2008240155
公开号：
AU2008240155B2
申请日:
2008.04.11
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention includes compositions and methods of making an activatedpolymeric nanoparticle for targeted drug delivery that includes a biocompatiblepolymer and an amphiphilic stabilizing agent non-covalently associated witha spacer compound that includes at least one electrophile that selectively reactswith any nucleophilic on a targeting agent and places the targeting agent on theexterior surface of a biodegradable nanoshell, wherein an active agent is loadedwith the nanoshell.
