ZHE JIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY;WU, ZHANGGUI
发明人:
WU, ZHANGGUI
申请号:
CA2711629
公开号:
CA2711629C
申请日:
2009.01.07
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to thienopyridazine compounds of formula (I),theirpharmaceutically acceptable salts or hydrates, wherein R1 and R2 areindependentlyH or C1-4 alkyl, R3 is a saturated or unsaturated 5- or 6- membered ringcontaining N,S or O, or its optical isomers, R4 is a halophenyl monosubstituted ordisubstituted atany position. The present invention provides the preparation methods of thesecompounds, pharmaceutical compositions containing these compounds and the usesof these compounds, particularly in treating cancer.(See Formula I)