ZHE JIANG MEDICINE CO., LTD XINCHANG PHARMACEUTICAL FACTORY;ZHANGGUI WU
发明人:
ZHANGGUI WU
申请号：
BRPI0907228
公开号：
BRPI0907228A2
申请日:
2009.01.07
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention relates to thienopyridazine compounds of formula (I), their pharmaceutically acceptable salts or hydrates, wherein R1 and R2 are independently H or C1-4 alkyl, R3 is a saturated or unsaturated 5- or 6- membered ring containing N, S or O, or its optical isomers, R4 is a halophenyl monosubstituted or disubstituted at any position. The present invention provides the preparation methods of these compounds, pharmaceutical compositions containing these compounds and the uses of these compounds, particularly in treating cancer.
