Fused aminodihydrothiazine derivatives

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专利权人:

Ltd.;Eisai R&D Management Co.

发明人:

Takaihsi, Mamoru,Ishida, Tasuku

申请号：

AU2012208348

公开号：

AU2012208348A1

申请日:

2012.01.19

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine； R is monofluoromethyl or difluoromethyl； and pharmaceutically acceptable salts thereof； which compound has an Αβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Αβ and typified by Alzheimer-type dementia.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/