FUSED AMINODIHYDROTHIAZINE DERIVATIVES USEFUL AS BACE INHIBITORS

• 收藏
• 分享

专利权人:

LTD.;EISAI R&D MANAGEMENT CO.

发明人:

HALL, ADRIAN,FARTHING, CHRISTOPHER NEIL,CASTRO PINEIRO, JOSE, LUIS

申请号：

SG2013041033

公开号：

SG190908A1

申请日:

2012.01.20

申请国别(地区):

SG

年份:

2013

代理人:

摘要：

The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine； A is CH or N； Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or -C≡N； and pharmaceutically acceptable salts thereof； which compound has an Αβ production inhibitory effect or a BACEl inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Αβ and typified by Alzheimer-type dementia.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/