Vincent PLASSAT,Benoit HILBOLD,Aurélia GALUS,Thomas POINTEAUX,Julien MEISSONNIER
申请号：
US16845830
公开号：
US20200323985A1
申请日:
2020.04.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure is directed to a pharmaceutical formulation intended for oral delivery of synthetic or natural poorly permeable molecules or salts/solvates thereof having a therapeutic activity. The pharmaceutical formulation can include a synthetic or natural poorly permeable molecule or salt or solvate thereof in an amount 0.01-10 wt. % of the total weight of the formulation； a lipophilic phase comprising triglycerides of fatty acids in an amount of 50-80 wt. % of the total weight of the formulation； and at least one lipophilic surfactant comprising partial esters of polyol and fatty acids in an amount of about 10-50 wt. % of the total weight of the formulation.
