Institute of Medical Support Technology; Academy of System Engineering; Academy of Military Science
发明人:
Jing GUAN,Jian YANG,Ying ZHANG,Feng TIAN,Jimin WU,Sheng DING,Zhihong LI,Chunlai WANG
申请号：
US16662774
公开号：
US20200316248A1
申请日:
2019.10.24
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to an alkyl chitosan-graphene oxide composite sponge and preparation method and application thereof. The alkyl chitosan-graphene oxide composite sponge provided by the present invention includes alkyl chitosan and graphene oxide absorbed on the alkyl chitosan, and the adsorbing capacity of the graphene oxide is 3-28 wt. %. In the present invention, alkyl chitosan is used as a matrix to combine graphene oxide and alkyl chitosan； the obtained composite sponge has excellent hemostatic performance and blood absorption capacity. Results of embodiments indicate that the in-vitro whole blood coagulation time is less than 58 s, the hemostasis time of a rabbit femoral artery hemorrhage model is less than 155 s, the hemorrhage mass is less than 5.4 g, and the hemostatic effect is superior to a pure alkyl chitosan sponge or graphene oxide powder when the composite sponge provided by the present invention is used for hemostasis.
