CHRISTIAN GEGE,CHRISTOPH STEENECK,GERALD KLEYMANN,OLAF KINZEL,THOMAS HOFFMANN
申请号:
BR112015002738
公开号:
BR112015002738A2
申请日:
2013.05.29
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The invention provides modulators for the orphan nuclear receptor ROR³ and methods for treating ROR³ mediated diseases by administering these novel ROR³ modulators to a human or a mammal in need thereof. Specifically, the present invention relates to compounds for use ROR³ modulators, wherein the compounds are carboxamide containing cyclic compounds of Formula ( 6 ) to Formula ( 9 ) and the enantiomers, diastereomers, tautomers, N-oxides, solvates and pharmaceutically acceptable salts thereof.