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פורמולציה ליפוזומלית לשימוש בטיפול בסרטן
专利权人:
NOVARTIS AG;LES LABORATOIRES SERVIER
发明人:
申请号:
IL26619819
公开号:
IL266198D0
申请日:
2019.04.23
申请国别(地区):
IL
年份:
2019
代理人:
摘要:
The invention relates to a pharmaceutical liposomal composition comprising 2-{[5-{3-chloro-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl}-6-(4-fluorophenyl)thieno [2,3-d]pyrimidin-4-yl]oxy}-3-(2-{[2-(2-methoxyphenyl)pyrimidin-4-yl]methoxy}phenyl) propanoic acid, referred to herein as 'Compound A', or a pharmaceutically acceptable salt thereof. More specifically the invention relates to a liposomal vehicle, an organic concentratecompositioncomprising Compound A, and a pharmaceutical composition for parenteral administration comprising liposomes and Compound A. Furthermore, the invention relates to the use of such compositions for the treatment of cancer. 'Compound A' as used herein includes all enantiomers, diastereoisomers, and atropisomers thereof, or mixtures thereof, and also optionally includes the pharmaceutically acceptable salts thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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