SHENG, QING,WANG, HUI-QIN,LI, FANG,LIANG, JINSHENG,CAO, ZHU ALEXANDER,MONAHAN, JOHN,VERSACE, RICHARD
申请号：
CA2890699
公开号：
CA2890699A1
申请日:
2013.11.06
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
A pharmaceutical combination comprising (a) a compound of formula (I), [Chemical formula should be inserted here as it appears on Abstract in paper form] or pharmaceutically acceptable salts thereof and (b) one or more at least one compound targeting, decreasing or inhibiting the intrinsic ATPase activity of Hsp90 and/or degrading, targeting, decreasing or inhibiting the Hsp90 client proteins via the ubiquitin proteosome pathway the uses of such combination in the treatment or prevention of proliferative diseases and methods of treating a subject suffering from a proliferative disease and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
