Qing Sheng,Hui-Qin Wang,Fang Li,Jinsheng Liang,Zhu Alexander Cao,John Monahan,Richard Versace
申请号:
US15184399
公开号:
US20160287605A1
申请日:
2016.06.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A pharmaceutical combination comprising (a) a compound of formula (I),or pharmaceutically acceptable salts thereof and (b) one or more at least one compound targeting, decreasing or inhibiting the intrinsic ATPase activity of Hsp90 and/or degrading, targeting, decreasing or inhibiting the Hsp90 client proteins via the ubiquitin proteosome pathway the uses of such combination in the treatment or prevention of proliferative diseases and methods of treating a subject suffering.