Sheng, Qing,Wang, Hui-Qin,Li, Fang,Liang, Jinsheng,Cao, Zhu Alexander,Monahan, John,Versace, Richard
申请号：
AU2013341271
公开号：
AU2013341271A1
申请日:
2013.11.06
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
A pharmaceutical combination comprising (a) a compound of formula (I), [Chemical formula should be inserted here as it appears on Abstract in paper form] or pharmaceutically acceptable salts thereof； and (b) one or more at least one compound targeting, decreasing or inhibiting the intrinsic ATPase activity of Hsp90 and/or degrading, targeting, decreasing or inhibiting the Hsp90 client proteins via the ubiquitin proteosome pathway； the uses of such combination in the treatment or prevention of proliferative diseases； and methods of treating a subject suffering from a proliferative disease； and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
