SAMMATUR, LEELADHAR,RAJAGOPALAN, RAJKANNAN,SHARMA, ARTHVAN,KALIAPERUMAL, VALARMATHY,WEIR, GENEVIEVE,STANFORD, MARIANNE,PENWELL, ANDREA,WEIR, GENEVIEVE MARY
申请号:
CA3069019
公开号:
CA3069019A1
申请日:
2017.11.09
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present disclosure relates to methods for preparing a dried preparation comprising lipids and a therapeutic agent by using lipid vesicle particles having a mean particle size of = 120 nm and a polydispersity index (PDI) of = 0.1. The present application also provides stable, water-free pharmaceutical compositions comprising one or more lipid-based structures having a single layer lipid assembly, at least one therapeutic agent, and a hydrophobic carrier, as well as methods of treatment, uses and kits relating thereto, such as for example for inducing an antibody and/or CTL immune response.