SAMMATUR, Leeladhar,RAJAGOPALAN, Rajkannan,SHARMA, Arthvan,KALIAPERUMAL, Valarmathy,WEIR, Genevieve,STANFORD, Marianne,PENWELL, Andrea
申请号：
AU2017438994
公开号：
AU2017438994A1
申请日:
2017.11.09
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The present disclosure relates to methods for preparing a dried preparation comprising lipids and therapeutic agents whereby the therapeutic agents are incorporated both before and after sizing of lipid vesicle particles to a mean particle size of ≤ 120 nm and a polydispersity index (PDI) of ≤0.1. The present application also provides stable, water-free pharmaceutical compositions comprising one or more lipid-based structures having a single layer lipid assembly, at least two therapeutic agents, and a hydrophobic carrier, as well as methods of treatment, uses and kits relating thereto, such as for example for inducing an antibody and/or CTL immune response.
