Macrocyclic LRRK2 kinase inhibitors

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专利权人:

IPSEN PHARMA S.A.S.;Oncodesign S.A.

发明人:

HOFLACK, Jan,BLOM, Petra

申请号：

DK12798824

公开号：

DK2760453T3

申请日:

2012.09.28

申请国别(地区):

DK

年份:

2016

代理人:

摘要：

The present invention relates to novel macrocylic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of LRRK2 (Leucine-Rich Repeat Kinase 2). Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine or diagnostic agent, in particular for the treatment and/or diagnosis of diseases characterized by LRRK2 kinase activity such as neurological disorders including Parkinson's disease and Alzheimer's disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/