IMMMUNOVACCINE TECHNOLOGIES INC.;IMMUNOVACCINE TECHNOLOGIES INC.
发明人:
SAMMATUR, LEELADHAR,RAJAGOPALAN, RAJKANNAN,SHARMA, ARTHVAN,KALIAPERUMAL, VALARMATHY,WEIR, GENEVIEVE,STANFORD, MARIANNE,PENWELL, ANDREA
申请号：
CA3091974
公开号：
CA3091974A1
申请日:
2017.11.09
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to methods for preparing a dried preparation comprising lipids and therapeutic agents whereby the therapeutic agents are incorporated both before and after sizing of lipid vesicle particles to a mean particle size of = 120 nm and a polydispersity index (PDI) of =0.1. The present application also provides stable, water-free pharmaceutical compositions comprising one or more lipid-based structures having a single layer lipid assembly, at least two therapeutic agents, and a hydrophobic carrier, as well as methods of treatment, uses and kits relating thereto, such as for example for inducing an antibody and/or CTL immune response.
