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磁性粒子含有医薬用原薬
专利权人:
戸田工業株式会社
发明人:
博多 俊之,川崎 浩史,植本 真次,堀石 七生
申请号:
JP2006165168
公开号:
JP5321772B2
申请日:
2006.06.14
申请国别(地区):
JP
年份:
2013
代理人:
摘要:

PROBLEM TO BE SOLVED: To obtain a raw medicine for magnetic particle-containing medicine, which produces in excellent reproducibility a magnetic particle-containing medicine that exhibits uniform functionality and is useful for diagnosis and treatment.

SOLUTION: The raw medicine for magnetic particle-containing medicine is a colloidal aseptic aqueous solution comprising monodispersed magnetic iron oxide fine particles having 5-30 nm average particle diameter of primary particles, 30-200 nm flocculated particle diameters, 35-90 Am2/kg saturation magnetization and 0-6.0 kA/m holding power. The raw medicine for magnetic particle-containing medicine is obtained by forming minute magnetic iron oxide particles, removing water-soluble by-product salts generated as by-products in a reaction from a reaction solution by washing with water by a routine procedure, purifying a colloidal aqueous solution of superparamagnetic iron oxide particles and replacing the dispersion medium of the purified colloidal aqueous solution with ultrapure water.

COPYRIGHT: (C)2007,JPO&INPIT

来源网站:
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