ANDREWS, Ian Paul;DAVIS, Tyler Andrew;SUDINI, Ravinder Reddy;CALANDRA, Nicholas;DERMAVANT SCIENCES GMBH
发明人:
ANDREWS, Ian Paul,CALANDRA, Nicholas,DAVIS, Tyler Andrew,SUDINI, Ravinder Reddy
申请号：
SG11202002576T
公开号：
SG11202002576TA
申请日:
2018.11.13
申请国别(地区):
SG
年份:
2020
代理人:
摘要：
The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
