ANDREWS, IAN PAUL,CALANDRA, NICHOLAS,DAVIS, TYLER ANDREW,SUDINI, RAVINDER REDDY
申请号:
CA3082115
公开号:
CA3082115A1
申请日:
2018.11.13
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.