Ian Paul Andrews,Nicholas Calandra,Tyler Andrew Davis,Ravinder Reddy Sudini
申请号：
US16189268
公开号：
US10647649B2
申请日:
2018.11.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
