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NOVEL CYCLIC PEPTIDE COMPOUND METHOD FOR PRODUCING SAME ANTI INFECTIVE AGENT ANTIBIOTIC CONTAINING FRACTION ANTIBIOTIC METHOD FOR PRODUCING ANTIBIOTIC ANTIBIOTIC PRODUCING MICROORGANISM AND ANTIBIOTIC PRODUCED BY SAME
专利权人:
发明人:
SEKIMIZU KAZUHISA,HAMAMOTO HIROSHI,MURAKAMI KAZUHISA
申请号:
IN10355/CHENP/2012
公开号:
IN2012CN10355A
申请日:
2012.12.12
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
123Disclosed are a novel compound which has a chemical structure different from that of a conventional medicament a novel microorganism which produces the novel compound and a novel compound which is also effective in multidrug resistant bacteria. Also disclosed is a novel compound which has a high therapeutic effect and can be expected to have a low hurdle for practical application by selecting a target compound from a lot of candidate compounds through evaluation for not only an antibacterial activity but also for a therapeutic effect. More specifically disclosed are a cyclic peptide compound represented by formula (1) (wherein R represents an acyl group having 7 8 or 9 carbon atoms which may have a substituent; R represents a methyl group or a hydrogen atom; and R represents an ethyl group or a methyl group) or a pharmaceutically acceptable salt thereof and a microorganism having an accession number of NITE BP 870 or a naturally or artificially mutated microorganism thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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