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NOVEL CYCLIC PEPTIDE COMPOUND, METHOD FOR PRODUCING SAME, ANTI-INFECTIVE AGENT, ANTIBIOTIC-CONTAINING FRACTION, ANTIBIOTIC, METHOD FOR PRODUCING ANTIBIOTIC, ANTIBIOTIC-PRODUCING MICROORGANISM, AND ANTIBIOTIC PRODUCED BY SAME
专利权人:
GENOME PHARMACEUTICALS INSTITUTE CO.; LTD.
发明人:
SEKIMIZU, KAZUHISA,HAMAMOTO, HIROSHI,MURAKAMI, KAZUHISA
申请号:
CA2799572
公开号:
CA2799572C
申请日:
2011.05.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Provided are: a novel compound having a structuredifferent from that of existing drugs a novel microorganismcapable of producing the novel compound and further a novelcompound effective to a multiple-drug-resistant bacterium. Toprovide a novel compound having a high therapeutic effect whichcan be expected to have a low hurdle for practical realizationby selecting an intended compound from many candidate compoundsbased not only on an antibacterial activity but also onevaluation including a therapeutic effect, a cyclic peptidecompound shown by the following formula (1) or apharmaceutically allowable salt thereof and a microorganismwith Accession No. NITE BP-870 or a microorganism mutatednaturally or artificially therefrom are provided.(In the formula (1) , R1 represents an acyl group having7 , 8, or 9 carbon atoms and optionally containing a substituentgroup R2 represents a methyl group or a hydrogen atom and R3represents an ethyl group or a methyl group.)92
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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