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Cyclic peptide compound, method for producing same, anti-infective agent, antibiotic-containing fraction, antibiotic, method for producing antibiotic, antibiotic-producing microorganism, and antibiotic produced by same
专利权人:
Kazuhisa Sekimizu
发明人:
Kazuhisa Sekimizu,Hiroshi Hamamoto,Kazuhisa Murakami
申请号:
US13699161
公开号:
US08754040B2
申请日:
2011.05.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are: a novel compound having a structure different from that of existing drugs a novel microorganism capable of producing the novel compound and further a novel compound effective to a multiple-drug-resistant bacterium. To provide a novel compound having a high therapeutic effect which can be expected to have a low hurdle for practical realization by selecting an intended compound from many candidate compounds based not only on an antibacterial activity but also on evaluation including a therapeutic effect, a cyclic peptide compound shown by the following formula (1) or a pharmaceutically allowable salt thereof and a microorganism with Accession No. NITE BP-870 or a microorganism mutated naturally or artificially therefrom are provided.(In the formula (1), R1 represents an acyl group having 7, 8, or 9 carbon atoms and optionally containing a substituent group R2 represents a methyl group or a hydrogen atom and R3 represents an ethyl group or a methyl group.)
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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