PHARMACEUTICAL FORMULATIONS BEING SALTS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE AND TREATMENT METHODS USING THE SAME
PROBLEM TO BE SOLVED: To provide: pharmaceutically useful formulations containing salts of compounds classified as Tachykinin compounds and being neuropeptide neurokinin-1 receptors [NK-1] receptors; and treatment methods using the formulations.SOLUTION: A pharmaceutical formulation contains a salt of a compound represented by the formula I, an excipient, one or more 5H-3 receptor antagonists, and further, corticosteroid. Also provided are treatment methods using the formulation.【課題】神経ペプチドニューロキニン-1受容体[NK-1]の受容体でタキキニン化合物に分類される化合物の塩を含む薬学的に有用な処方物と、それを使用した処置方法の提供。【解決手段】式Iで表される化合物の塩と、賦形剤と1つ以上の5H-3受容体拮抗薬、更にコルチコステロイドとを含有する薬学的処方物、及び当該剤形を使用した処置方法。【選択図】図1