The invention aims to provide peoples diphtheria toxin class ADP- ribosyltransferases of inhibitor, such as ARTD10, it is used as drug. Its another purpose is to provide external as single assembly detail ribosyltransferase (mARTD) inhibitor of people to compound. It is a discovery of the invention that people ARTD10, belongs to a kind of enzyme family and be attached to carcinobiology, can specifically inhibit, disclosed compound, such as 4,4 -oxydibenzamide are included in the invention by benzamide.