Doses containing pregnane glycosides alone, and in combination with severalother compounds for treatment of disorders/conditions such as obesity, lowBMR, hyperglycaemia, hypertension, hypercholesterolemia, Type (2) diabetes,migraine, osteo-arthritis and joint degradation/inflammation, clinicaldepression, menopausal syndrome, ageing syndrome, circulation syndrome,capillary degeneration, reduced cognitive and memory function, hearing loss,sexual dysfunction and others are disclosed. Doses are also provided for theregulation/improvement of various physiologicalparameters/conditions/functions associated with said disorders and others suchas skin condition, joint mobility, mood, memory function and recall, lean bodymass, stamina, libido and others. The preferred glycoside is a caralluma plantextract containing a synergical mixture of the pregnane glycosides,caratubersides and boucerosides containing 90-95% of the former. Combinationsthereof with the extracts of Green tea, Fenugreek, Ashwagandha, Shilajith,Commiphora Mukul, Garcinia, Hibiscus Subdarifa, Coccinia, Bittergourd,Cinnamon, Liquorice, Red clover, Hops flowers, Pomegranate and withGlucosamine, Zinc monomethionine, Citrus bioflavonoids, Rutin, Bamboo silica,Shilajith, Saponin glycosides and the biders of caralluma, and selenium aredisclosed.
