Elyse BOURQUE,Mario A. CABRERA-SALAZAR,Cassandra CELATKA,Seng H. CHENG,Bradford Hirth,Andrew GOOD,Katherine JANCSICS,John MARSHALL,Markus Metz,Ronald K. SCHEULE,Renato SKERLJ,Yibin XIANG,Zhong ZHAO,Jo
申请号:
US15490385
公开号:
US20180065957A1
申请日:
2017.04.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.