PROBLEM TO BE SOLVED: To provide a solid preparation, having an improved elution property by a method which is simple in formulating operation for a physiologically active substance having ultrahigh water solubility, forming an adhesive gel layer on the particle surface by contact with water, and delaying disintegration and elution.SOLUTION: There is provided the solid preparation having the improved elution property of the physiologically active substance by including the physiologically active substance extremely readily soluble in water and a water-soluble saccharide or a sugar alcohol.COPYRIGHT: (C)2013,JPO&INPIT【課題】水溶性が極めて高く、水との接触により粒子表面に粘着性のゲル層を形成し、崩壊、溶出が遅延する生理活性物質について、製剤操作上簡便な方法により、溶出性が改善された固形製剤を提供すること【解決手段】 水に極めて溶けやすい生理活性物質及び水溶性の糖類又は糖アルコールを含有させることにより、生理活性物質の溶出性が改善された固形製剤を提供する。【選択図】なし
