Method reaches quick 3D printing microneedle patch. 3D printing processes are placed including printing multiple micro holes and cold plate/platform micropin support slice (film). The speed that cold micropin support sheet and program rate injection are printed in the micropin forming material of solution or aqueous solution is promoted from nozzle and nozzle. Micro- tip of shape is determined in injection rate and promotion speed. Cold drying of the micropin newly printed, with two methods it is dry (temperature close to freezing point water or it is dry after freeze-thaw treatment micropin.