SABOULARD DIDIER,PLANTIER JEAN LUC,DELCOURT MARC,NEGRIER CLAUDE,MENGUY THIERRY,BLESA STPHANE,MARIN SYLVIE
申请号:
IN5909/DELNP/2009
公开号:
IN2009DN05909A
申请日:
2009.09.15
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention relates to improved human FVIII variants having at least one substitution in the A2 and/or C2 domain. The present invention also relates to their uses in the treatment of hemophilia A, particularly in patients with inhibitors.