HAANING, JESPER MORTENSEN,ANDERSEN, KIM VILBOUR,BORNAES, CLAUS
申请号：
CA2529828
公开号：
CA2529828C
申请日:
2004.06.18
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Gla domain variants of human Factor VII or human Factor VIIa, comprising 1-15amino acid modifications relative to human Factor VII or human Factor VIIa,wherein a hydrophobic amino acid residue has been introduced by substitutionin position 34, or having an amino acid substitution in position 36, or havingamino acid substitutions in positions 10 and 32 and at least one further aminoacid substitution in a position selected from 74, 77 and 116.
