HAANING, JESPER, MORTENSEN,ANDERSEN, KIM, VILBOUR,BORNAES, CLAUS
申请号:
HK07100447.2
公开号:
HK1095357B
申请日:
2007.01.12
申请国别(地区):
HK
年份:
2012
代理人:
摘要:
Gla domain variants of human Factor VII or human Factor VIIa, comprising 1-15 amino acid modifications relative to human Factor VII or human Factor VIIa, wherein a hydrophobic amino acid residue has been introduced by substitution in position 34; or having an amino acid substitution in position 36; and use of the variants for the treatment of intracerebral haemorrhage (ICH) or trauma.