Christian GERDES,Christian KLEIN,Valeria G. NICOLINI,Pablo UMANA
申请号：
US16807129
公开号：
US20200197492A1
申请日:
2020.03.02
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides combinations of (a) an immunoconjugate comprising a first antibody engineered to have reduced effector function and an effector moiety, and (b) a second antibody engineered to have increased effector function, for use in treating a disease in an individual in need thereof. Further provided are pharmaceutical compositions comprising the combinations, and methods of using them.
