Gerdes, Christian,Klein, Christian,Nicolini, Valeria G.,Umana, Pablo
申请号：
AU2013301582
公开号：
AU2013301582A1
申请日:
2013.08.05
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention provides combinations of (a) an immunoconjugate comprising a first antibody engineered to have reduced effector function and an effector moiety, and (b) a second antibody engineered to have increased effector function, for use in treating a disease in an individual in need thereof. Further provided are pharmaceutical compositions comprising the combinations, and methods of using them.
