Christian Gerdes,Christian Klein,Valeria G. Nicolini,Pablo Umana
申请号：
US13961649
公开号：
US09526797B2
申请日:
2013.08.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides combinations of (a) an immunoconjugate comprising a first antibody engineered to have reduced effector function and an effector moiety, and (b) a second antibody engineered to have increased effector function, for use in treating a disease in an individual in need thereof. Further provided are pharmaceutical compositions comprising the combinations, and methods of using them.
