Campbell, John Emmerson,Duncan, Kenneth William,Foley, Megan Alene,Harvey, Darren Martin,Kuntz, Kevin Wayne,Mills, James Edward John,Munchhof, Michael John
申请号：
AU2017250369
公开号：
AU2017250369A1
申请日:
2017.04.17
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present disclosure relates to amine-substituted aryl or heteroaryl compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., sickle cell anemia) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering an amine-substituted aryl or heteroaryl compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
