CAMPBELL, John Emmerson,DUNCAN, Kenneth William,FOLEY, Megan Alene,HARVEY, Darren Martin,KUNTZ, Kevin Wayne,MILLS, James Edward John,MUNCHHOF, Michael John
申请号：
SG11201808799S
公开号：
SG11201808799SA
申请日:
2017.04.17
申请国别(地区):
SG
年份:
2018
代理人:
摘要：
The present disclosure relates to amine-substituted aryl or heteroaryl compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., sickle cell anemia) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering an amine-substituted aryl or heteroaryl compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
