A clamping and cutting mechanism for an ampoule bottle (1). The clamping and cutting mechanism comprises a base, two brackets (2) being provided on the base, each of the brackets being provided with a splint (5) and a cutter (6); the two splints being oppositely arranged to form a clamping part, and a distance between the two splints being adjustable and fitting a bottle body (12) of an ampoule bottle; the two cutters being oppositely arranged to form a cutting part, and a distance between the two cutters being adjustable and fitting a neck (13) of the ampoule bottle. The clamping and cutting mechanism integrates the functions of the clamping part and the cutting part onto the two brackets on one base, the two splints and the cutters on the two brackets being moveable relative to each other simultaneously, being able to respectively clamp the ampoule bottle and cut the neck of the ampoule bottle. The structure of the clamping and cutting mechanism is simple and compact, saving the volume, saving energies, and
