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DÉRIVÉ DE MORPHINANE
专利权人:
Ltd.;Nippon Chemiphar Co.
发明人:
NAGASE, Hiroshi,FUJII, Hideaki,SAITOH, Akiyoshi,NAKATA, Eriko,HIROSE, Masaaki,OOI, Isao,HAYASHIDA, Kohei
申请号:
EP17839452
公开号:
EP3498711A4
申请日:
2017.08.08
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
A compound represented by the following general formula (I),wherein Rrepresents hydrogen, Calkyl, cycloalkylalkyl where the cycloalkyl moiety has 3 to 6 carbon atoms and the alkylene moiety has 1 to 5 carbon atoms, or the like,Rrepresents a 4- to 7-membered saturated heterocycle containing one or two heteroatoms which may be the same or different and are selected from N, O, and S, and two or more carbon atoms as ring-constituting atoms,the heterocycle may be substituted with a substituent such as an oxo group,Rbinds to Y via a carbon atom as a ring-constituting atom of R,R, R, and R, which are the same or different, represent hydrogen; hydroxy; or the like,Rand R, which are the same or different, represent hydrogen or the like,Rand R, which are the same or different, represent hydrogen or the like,Rand R, which are the same or different, represent hydrogen or the like,X represents O or CH, andY represents C(= O) or the like),a tautomer of the compound, a stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof is used as an anxiolytic, an antidepressant, or the like.
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