T CELL RECEPTORS DIRECTED AGAINST THE PREFERENTIALLY EXPRESSED ANTIGEN OF MELANOMA AND USES THEREOF

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专利权人:

Leiden University Medical Center

发明人:

Mirjam H.M. Heemskerk,J.H. Frederik Falkenburg

申请号：

US16521430

公开号：

US20200054678A1

申请日:

2019.07.24

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The technology relates in part to compositions and methods for inducing an immune response against the Preferentially Expressed Antigen of Melanoma (PRAME). Provided are methods for treating hyperproliferative diseases by inducing an immune response against PRAME antigen； the immune response may be induced by specifically targeting PRAME-expressing cells using T cell receptors directed against PRAME.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/