ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LUMC);LEIDEN UNIVERSITY MEDICAL CENTER
发明人:
FALKENBURG, J.H. FREDERIK,HEEMSKERK, MIRJAM H.M.
申请号：
CA2978171
公开号：
CA2978171A1
申请日:
2016.03.09
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The technology relates in part to compositions and methods for inducing an immune response against the Preferentially Expressed Antigen of Melanoma (PRAME). Provided are methods for treating hyperproliferative diseases by inducing an immune response against PRAME antigen； the immune response may be induced by specifically targeting PRAME-expressing cells using T cell receptors directed against PRAME.
