STICHTING HET NEDERLANDS KANKER INSTITUUT;SLOTERVAART PARTICIPATIES BV
发明人:
BEIJNEN, JACOB HENDRIK,SCHELLENS, JOHANNES HENRICUS MATTHIAS,MOES, JOHANNES,NUIJEN, BASTIAAN
申请号:
CA2696622
公开号:
CA2696622C
申请日:
2008.08.22
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Pharmaceutical compositions and methods for the treatment of neoplasticdisease and comprising the combinationof a taxane, such as docetaxel, with a CYP3A4 inhibitor, such as ritonavir.Methods of treatment of neoplastic disease incorporatingthe administration of a taxane and the administration of a CYP3A4 inhibitor,either simultaneously or separately, are also included.Further, kits for carrying out the methods are included. Solid pharmaceuticaltaxane compositions for oral administrationcomprising a substantially amorphous taxane, a carrier and a surfactant arealso included.