The present invention relates to topical personal care and skin care compositions comprising: a) a safe and effective amount of a tetrapeptide selected from the group of tetrapeptides with the motif GX 1 X 2 G, PX 1 X 2 P, or PX 1 X 2 K, derivatives thereof, and mixtures thereof； b) a safe and effective amount of at least one additional active ingredient selected from the group consisting of hydroxy acids, radical scavengers, UV absorbers, vitamins, anti-aging actives, barrier lipids, desquamatory actives, retinoids, anti-acne actives, tanning actives, anti-cellulite actives, antiinflammatory actives, antimicrobial actives, antifungal actives, skin lightening agents, skin energizing agents, skin healing agents, moisturizing actives, and mixtures thereof； and c) a dermatologically acceptable carrier.
