BIRSNER, ULRICH,JUMAA, HASSAN,KLAPPROTH, HOLGER,KESSEMEIER, MARC A.
申请号：
CA3070847
公开号：
CA3070847A1
申请日:
2018.07.05
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to the field of producing, identifying and selecting biological binding molecules, such as antibodies or fragments thereof, as well as diagnostic methods using same within the context of diagnosing cancer diseases, such as, in particular, malignant B-cell neoplasms.canThe binding molecules are able to selectively bind to autonomously active or autonomously activated B-cell receptors, wherein the autonomously active or autonomously activated B-cell receptors are characterised by the presence of structural domains, to which the binding molecule selectively binds and which bring about the autonomously active or autonomously activated state of the B-cell receptors.
