A route guidance and obstacle avoidance system for the visually impaired includes a main body assembly worn around the body of the user and a headset assembly worn around the head of the user. The system incorporates obstacle avoidance technology and navigation technology to generate a 3D audio output to a user so as to generate an audible virtual environment reflective of the physical environment of the user. The assemblies include line of sight sensors, a central processing unit, a navigation module, and a camera assembly. Obstacles are detected and classified with a location and distance, and are concurrently processed with real time navigation that is adjusted to instruct not only how to get to a location but also how to avoid obstacles.