A vascular access device ultrasound guidance system which provides a novel ultrasound imaging head interface for vessel access. The system comprises a fitted basket/VAD guide for attachment to a hand held ultrasound transducer. The VAD guide, being integrally molded to the fitted basket, comprises a releasible guide assembly for a VAD needle guide. In addition, the needle guide assembly comprises means for anchoring the VAD to a patients skin following successful insertion. A magnetic needle guide system is disclosed. A fluid sampling device which integrates needle guidance and, safety needle capture in a single guide head is also disclosed.
