CRAGG, Mark,GLENNIE, Martin,ROGHANIAN, Ali,BEERS, Stephen,JOHNSON, Peter,LIM, Sean,FRENDEUS, Björn,TEIGE, Ingrid
申请号:
DK11760819
公开号:
DK2606068T3
申请日:
2011.08.19
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The invention provides a method of treating a patient having target cells that express Fc³RIIb, the method comprising administering (i) an antibody molecule that specifically binds a surface antigen of the target cell, which antibody molecule has an Fc domain capable of binding Fc³RIIb; in combination with (ii) an agent that prevents or reduces binding between the Fc domain of the antibody molecule and Fc³RIIb; characterized in that the patient is selected on the basis that their target cells express an elevated level of Fc³RIIb.