CRAGG MARK,GLENNIE MARTIN,ROGHANIAN ALI,BEERS STEPHEN,JOHNSON PETER,LIM SEAN,FRENDEUS BJÖRN,TEIGE INGRID
申请号：
IN1124/DELNP/2013
公开号：
IN2013DN01124A
申请日:
2013.02.06
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The invention provides a method of treating a patient having target cells that express FcyRIIb the method comprising administering (i) an antibody molecule that specifically binds a surface antigen of the target cell which antibody molecule has an Fc domain capable of binding FcyRIIb in combination with (ii) an agent that prevents or reduces binding between the Fc domain of the antibody molecule and FcyRIIb characterized in that the patient is selected on the basis that their target cells express an elevated level of FcyRIIb.
