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FLUORESCENCE-DETECTED ASSAYS ON MICROFLUIDIC CHIPS
专利权人:
ONE DROP DIAGNOSTICS SÀRL
发明人:
GERVAIS, LUC,ZIEGLER, JÖRG,DESCHARMES, NICOLAS
申请号:
WO2015EP54643
公开号:
WO2015132347(A1)
申请日:
2015.03.05
申请国别(地区):
世界知识产权组织国际局
年份:
2015
代理人:
摘要:

An assay unit for carrying-out fluorescence-detected assays on one or more physiological samples, comprises a microfluidic chip with a microfluidic system that is able to convey a physiological sample or analyte solution through one or more microfluidic channels (30) arranged on the chip, and a photonic system with two or more rectangular waveguide structures (62, 66, 63) arranged on the chip that are able to guide excitation light (64, 65) in the near IR, visible, or near UV range. The one or more microfluidic channels and the two or more waveguide structures cross each other at a detection site (26). In an assay area (32), where a certain microfluidic channel and a certain waveguide structure cross each other, one or more lateral surfaces of the core of the waveguide structure (66) at least partially face the inner volume of the microfluidic channel, such that an evanescent field of light guided the waveguide structure overlaps with a certain part of the inner volume of the microfluidic channel. In the a

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