An interbody fusion device related to implants for orthopedic surgery has a hollow skeleton made of titanium alloy to hold nonstructural cancellous bone graft. The skeleton is a U-shaped plate, whose front wall is disposed with holes. The upper and the lower end of the bottom of the U-shaped plate have inclined holes of ladder shape. The bigger end of the inclined hole is placed on the bottom surface of the bottom of the U-shaped plate, and the smaller end of the inclined hole is placed on the corresponding surface of the bottom of the U-shaped plate; the inclined hole of the U-shaped plate is disposed with screw inside. The present invention has small volume and the vertebra is partial removal, so it is more reliable for interbody fusion.